Positive staining for cellulose in oral pulse granuloma.
Oral Surg Oral Med Oral Pathol Oral Radiol
; 123(4): 464-467, 2017 Apr.
Article
en En
| MEDLINE
| ID: mdl-28189527
ABSTRACT
OBJECTIVE:
Oral pulse granuloma (OPG) is an oral inflammatory lesion characterized by the presence of hyaline rings with numerous multinucleated giant cells. The etiopathogenesis of this lesion is thus far unclear, as is the composition of the hyaline rings. Our aim was to investigate whether the hyaline rings contain cellulose. STUDYDESIGN:
Using a newly developed staining method for cellulose, we studied 18 histologic samples diagnosed as OPG, in addition to 3 samples originally diagnosed as "normal" foreign body reactions. In our study, visualization of cellulose is based on its specific binding to the carbohydrate binding module of ß-1,4-glycanase.RESULTS:
All samples diagnosed as OPG were positive for cellulose staining localized in hyaline rings. In addition, 1 lesion (of 3), first diagnosed as a foreign body reaction without the presence of hyaline rings, was positive for cellulose by horseradish peroxidase staining.CONCLUSIONS:
We show for the first time that cellulose is present in OPG lesions, indicating that cellulose might be the initial cause of formation of these lesions.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Coloración y Etiquetado
/
Granuloma de Cuerpo Extraño
/
Celulosa
/
Enfermedades de la Boca
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Oral Surg Oral Med Oral Pathol Oral Radiol
Año:
2017
Tipo del documento:
Article
País de afiliación:
Finlandia