Enhancement of ß-Globin Gene Expression in Thalassemic IVS2-654 Induced Pluripotent Stem Cell-Derived Erythroid Cells by Modified U7 snRNA.

Phanthong, Phetcharat; Borwornpinyo, Suparerk; Kitiyanant, Narisorn; Jearawiriyapaisarn, Natee; Nuntakarn, Lalana; Saetan, Jirawat; Nualkaew, Tiwaporn; Sa-Ngiamsuntorn, Khanit; Anurathapan, Usanarat; Dinnyes, Andras; Kitiyanant, Yindee; Hongeng, Suradej

Phanthong, Phetcharat; Borwornpinyo, Suparerk; Kitiyanant, Narisorn; Jearawiriyapaisarn, Natee; Nuntakarn, Lalana; Saetan, Jirawat; Nualkaew, Tiwaporn; Sa-Ngiamsuntorn, Khanit; Anurathapan, Usanarat; Dinnyes, Andras; Kitiyanant, Yindee; Hongeng, Suradej.

Afiliación

Phanthong P; Departments of Anatomy.
Borwornpinyo S; Stem Cell Research Group.
Kitiyanant N; Biotechnology.
Jearawiriyapaisarn N; Excellent Center for Drug Discovery, Faculty of Science, Mahidol University, Bangkok, Thailand.
Nuntakarn L; Stem Cell Research Group.
Saetan J; Thalassemia Research Center.
Nualkaew T; Departments of Obstetrics and Gynecology.
Sa-Ngiamsuntorn K; Anatomy Department, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.
Anurathapan U; Thalassemia Research Center.
Dinnyes A; Department of Biochemistry, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Kitiyanant Y; Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Hongeng S; Biotalentum Ltd, Godollo, Hungary.

Stem Cells Transl Med ; 6(4): 1059-1069, 2017 04.

Article en En | MEDLINE | ID: mdl-28213976

Asunto(s)

Células Eritroides/citología; Células Eritroides/metabolismo; Expresión Génica/genética; Células Madre Pluripotentes Inducidas/citología; ARN Nuclear Pequeño/genética; Globinas beta/genética; Animales; Humanos; Células Madre Pluripotentes Inducidas/metabolismo; Empalme del ARN/genética; Empalme del ARN/fisiología; Transcriptoma/genética; Talasemia beta/genética; Talasemia beta/metabolismo

Palabras clave

Induced pluripotent stem cell; Induced pluripotent stem cell-derived erythroblast; U7 snRNA; ß-Thalassemia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Nuclear Pequeño / Expresión Génica / Células Eritroides / Globinas beta / Células Madre Pluripotentes Inducidas Límite: Animals / Humans Idioma: En Revista: Stem Cells Transl Med Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido

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