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Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function.
Burkard, Christine; Lillico, Simon G; Reid, Elizabeth; Jackson, Ben; Mileham, Alan J; Ait-Ali, Tahar; Whitelaw, C Bruce A; Archibald, Alan L.
Afiliación
  • Burkard C; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
  • Lillico SG; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
  • Reid E; The Pirbright Institute, Ash Road, Pirbright, Woking, United Kingdom.
  • Jackson B; The Pirbright Institute, Ash Road, Pirbright, Woking, United Kingdom.
  • Mileham AJ; Genus plc, DeForest, Wisconsin, United States of America.
  • Ait-Ali T; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
  • Whitelaw CB; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
  • Archibald AL; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
PLoS Pathog ; 13(2): e1006206, 2017 02.
Article en En | MEDLINE | ID: mdl-28231264
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de Superficie Celular / Virus del Síndrome Respiratorio y Reproductivo Porcino / Síndrome Respiratorio y de la Reproducción Porcina / Macrófagos Límite: Animals Idioma: En Revista: PLoS Pathog Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de Superficie Celular / Virus del Síndrome Respiratorio y Reproductivo Porcino / Síndrome Respiratorio y de la Reproducción Porcina / Macrófagos Límite: Animals Idioma: En Revista: PLoS Pathog Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido