Intrinsic, adaptive and acquired antimicrobial resistance in Gram-negative bacteria.
Essays Biochem
; 61(1): 49-59, 2017 02 28.
Article
en En
| MEDLINE
| ID: mdl-28258229
ABSTRACT
Gram-negative bacteria are responsible for a large proportion of antimicrobial-resistant infections in humans and animals. Among this class of bacteria are also some of the most successful environmental organisms. Part of this success is their adaptability to a variety of different niches, their intrinsic resistance to antimicrobial drugs and their ability to rapidly acquire resistance mechanisms. These mechanisms of resistance are not exclusive and the interplay of several mechanisms causes high levels of resistance. In this review, we explore the molecular mechanisms underlying resistance in Gram-negative organisms and how these different mechanisms enable them to survive many different stress conditions.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Farmacorresistencia Microbiana
/
Adaptación Fisiológica
/
Bacterias Gramnegativas
/
Antiinfecciosos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Essays Biochem
Año:
2017
Tipo del documento:
Article
País de afiliación:
Irán