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DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy.
Shadle, Sean C; Zhong, Jun Wen; Campbell, Amy E; Conerly, Melissa L; Jagannathan, Sujatha; Wong, Chao-Jen; Morello, Timothy D; van der Maarel, Silvère M; Tapscott, Stephen J.
Afiliación
  • Shadle SC; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington, United States of America.
  • Zhong JW; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • Campbell AE; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • Conerly ML; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • Jagannathan S; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • Wong CJ; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • Morello TD; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • van der Maarel SM; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • Tapscott SJ; Computational Biology Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
PLoS Genet ; 13(3): e1006658, 2017 03.
Article en En | MEDLINE | ID: mdl-28273136
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rabdomiosarcoma / ARN Bicatenario / Proteínas Proto-Oncogénicas c-myc / Apoptosis / Proteínas de Homeodominio / Distrofia Muscular Facioescapulohumeral Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rabdomiosarcoma / ARN Bicatenario / Proteínas Proto-Oncogénicas c-myc / Apoptosis / Proteínas de Homeodominio / Distrofia Muscular Facioescapulohumeral Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos