Declining antibody levels after hepatitis B vaccination in Down syndrome: A need for booster vaccination?
J Med Virol
; 89(9): 1682-1685, 2017 09.
Article
en En
| MEDLINE
| ID: mdl-28322457
ABSTRACT
We determined the anti-HBs titer in 227 children of all ages with Down syndrome (DS). Only 48.1% (95%CI 35.1-61.3) of the DS children aged 7-10 years and 31.9% (95%CI 22.1-43.6) of the DS children aged >10 years had a protective anti-HBs titer (≥10 IU/L). The geometric mean anti-HBs titer was significantly lower in the DS children; this suggests booster vaccination for HBV may be needed.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Virus de la Hepatitis B
/
Vacunas contra Hepatitis B
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Síndrome de Down
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Hepatitis B
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Anticuerpos contra la Hepatitis B
Tipo de estudio:
Clinical_trials
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Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Male
Idioma:
En
Revista:
J Med Virol
Año:
2017
Tipo del documento:
Article
País de afiliación:
Países Bajos