Molecular connections of obesity and aging: a focus on adipose protein 53 and retinoblastoma protein.
Biogerontology
; 18(3): 321-332, 2017 06.
Article
en En
| MEDLINE
| ID: mdl-28357524
ABSTRACT
Obesity is an induced health problem that human beings have been facing with non-optimal treatment so far. Humans are on average getting fatter with age, and obesity and aging interact each other to shorten lifetime and decrease life quality. Obesity also causes several aging related-disorders such as cancer, strokes, cardiovascular disease, high blood pressure and type 2 diabetes. So, the molecular connections between aging and obesity are promising targets for bio-medical researches and innovative therapies of many health problems. In this review, we discuss the findings of adipose p53 and Rb-two central molecular linkages between aging and obesity-on lipid metabolism and obesity.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Tejido Adiposo
/
Proteína p53 Supresora de Tumor
/
Proteína de Retinoblastoma
/
Obesidad
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Biogerontology
Asunto de la revista:
GERIATRIA
Año:
2017
Tipo del documento:
Article
País de afiliación:
Vietnam