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Development of a One-Pot Synthetic Method for Multifunctional Oxazole Derivatives Using Isocyanide Dichloride.
Soeta, Takahiro; Matsumoto, Akihiro; Sakata, Yoko; Ukaji, Yutaka.
Afiliación
  • Soeta T; Division of Material Sciences, Graduate School of Natural Science and Technology, Kanazawa University , Kakuma, Kanazawa 920-1192, Japan.
  • Matsumoto A; Division of Material Sciences, Graduate School of Natural Science and Technology, Kanazawa University , Kakuma, Kanazawa 920-1192, Japan.
  • Sakata Y; Division of Material Sciences, Graduate School of Natural Science and Technology, Kanazawa University , Kakuma, Kanazawa 920-1192, Japan.
  • Ukaji Y; Division of Material Sciences, Graduate School of Natural Science and Technology, Kanazawa University , Kakuma, Kanazawa 920-1192, Japan.
J Org Chem ; 82(9): 4930-4935, 2017 05 05.
Article en En | MEDLINE | ID: mdl-28402117
ABSTRACT
A one-pot synthetic method was developed for multifunctional dihydrooxazole and oxazole derivatives. New reaction sequences were developed involving the formation of isocyanide dichloride, an aldol-type reaction with aldehydes, and a nucleophilic addition-elimination reaction, which efficiently afforded the dihydrooxazole and oxazole scaffolds.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Org Chem Año: 2017 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Org Chem Año: 2017 Tipo del documento: Article País de afiliación: Japón