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Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode.
Hu, Chen; Wang, Aoli; Wu, Hong; Qi, Ziping; Li, Xixiang; Yan, Xiao-E; Chen, Cheng; Yu, Kailin; Zou, Fengming; Wang, Wenchao; Wang, Wei; Wu, Jiaxin; Liu, Juan; Wang, Beilei; Wang, Li; Ren, Tao; Zhang, Shanchun; Yun, Cai-Hong; Liu, Jing; Liu, Qingsong.
Afiliación
  • Hu C; High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China.
  • Wang A; University of Science and Technology of China, Hefei, Anhui 230036, P. R. China.
  • Wu H; High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China.
  • Qi Z; University of Science and Technology of China, Hefei, Anhui 230036, P. R. China.
  • Li X; High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China.
  • Yan XE; CHMFL-HCMTC Target Therapy Joint Laboratory, Hefei, Anhui 230031, P. R. China.
  • Chen C; High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China.
  • Yu K; CHMFL-HCMTC Target Therapy Joint Laboratory, Hefei, Anhui 230031, P. R. China.
  • Zou F; High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China.
  • Wang W; CHMFL-HCMTC Target Therapy Joint Laboratory, Hefei, Anhui 230031, P. R. China.
  • Wang W; Institute of Systems Biomedicine, Department of Biophysics, Beijing Key Laboratory of Tumor Systems Biology and Center for Molecular and Translational Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China.
  • Wu J; High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China.
  • Liu J; University of Science and Technology of China, Hefei, Anhui 230036, P. R. China.
  • Wang B; High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China.
  • Wang L; University of Science and Technology of China, Hefei, Anhui 230036, P. R. China.
  • Ren T; High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China.
  • Zhang S; CHMFL-HCMTC Target Therapy Joint Laboratory, Hefei, Anhui 230031, P. R. China.
  • Yun CH; High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China.
  • Liu J; CHMFL-HCMTC Target Therapy Joint Laboratory, Hefei, Anhui 230031, P. R. China.
  • Liu Q; High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China.
Oncotarget ; 8(11): 18359-18372, 2017 Mar 14.
Article en En | MEDLINE | ID: mdl-28407693
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Inhibidores de Proteínas Quinasas / Receptores ErbB / Neoplasias Pulmonares Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Inhibidores de Proteínas Quinasas / Receptores ErbB / Neoplasias Pulmonares Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos