Low-Intensity Pulsed Ultrasound-Induced Spinal Fusion is Coupled with Enhanced Calcitonin Gene-Related Peptide Expression in Rat Model.
Ultrasound Med Biol
; 43(7): 1486-1493, 2017 07.
Article
en En
| MEDLINE
| ID: mdl-28457632
ABSTRACT
Low-intensity pulsed ultrasound (LIPUS) has been found to accelerate fracture healing. In this study, we analyzed the role of calcitonin gene-related peptide (CGRP) in a rat spinal fusion model treated with LIPUS. The results revealed that LIPUS significantly increases bone formation, and the process was coupled with elevated CGRP innervation. CGRP was located in fibrous tissue, closely surrounding the allograft and newly formed cartilage. The density of CGRP peaked at week 3 after surgery in both the control (non-LIPUS-treated) and LIPUS-treated groups. These results suggest that LIPUS might accelerate spinal fusion by promoting sensory nerve fiber innervation.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fusión Vertebral
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Terapia por Ultrasonido
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Péptido Relacionado con Gen de Calcitonina
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Ondas Ultrasónicas
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Vértebras Lumbares
Límite:
Animals
Idioma:
En
Revista:
Ultrasound Med Biol
Año:
2017
Tipo del documento:
Article
País de afiliación:
China