Increased image quality and reduced radiation dose and contrast media volume: a holistic approach to intracranial CTA.
Clin Radiol
; 72(9): 797.e11-797.e16, 2017 Sep.
Article
en En
| MEDLINE
| ID: mdl-28477959
ABSTRACT
AIM:
To investigate the dose-length product (DLP) during intracranial computed tomography angiography (CTA) using a patient-specific contrast formula. MATERIALS ANDMETHODS:
Intracranial CTA was performed on 120 patients using 64-channel CT. Patients were subjected in equal numbers to one of two acquisitions/contrast medium protocols. Protocol A, consisted of 80 ml contrast medium and protocol B, involved a novel contrast medium formula. In each protocol, contrast medium and saline were injected at a flow rate of 4.5 ml/s. The DLP and contrast volume (CV) were measured between each protocol and the data obtained were compared using two-tailed independent t-test.RESULTS:
Mean arterial vessel attenuation was up to 56% (p<0.01) higher using protocol B compared with A. In the venous system, the mean vessel attenuation was significantly lower in protocol B than A with a maximum reduction of 93% (p<0.001). The mean CV was significantly lower in protocol B (53±10 ml) compared to A (80±1 ml, p<0.001). The scan time was equal in each protocol (B, 4.22±1.2 seconds; A, 4.01±1.3 seconds). A significant reduction in mean DLP was demonstrated in protocol B (3.99±0.22 mSv) compared to A (4.74±0.22 mSv; p=0.02).CONCLUSION:
A significant reduction in CV and DLP during intracranial CTA can be achieved when employing a patient-specific contrast medium formula.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dosis de Radiación
/
Yohexol
/
Circulación Cerebrovascular
/
Medios de Contraste
/
Accidente Cerebrovascular
/
Angiografía por Tomografía Computarizada
Tipo de estudio:
Clinical_trials
/
Observational_studies
Límite:
Female
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Humans
/
Male
Idioma:
En
Revista:
Clin Radiol
Año:
2017
Tipo del documento:
Article
País de afiliación:
Australia