The relationship between circulating concentrations of interleukin 17 and C reactive protein in chronic spontaneous urticaria.
Allergy Asthma Clin Immunol
; 13: 25, 2017.
Article
en En
| MEDLINE
| ID: mdl-28491102
ABSTRACT
BACKGROUND:
Up-regulation of interleukin 17 (IL-17) family cytokines and acute phase response have been observed in patients with chronic spontaneous urticaria (CSU). It has been demonstrated that IL-17 stimulates C-reactive protein (CRP) expression.AIM:
To determine relationship between circulating concentrations of IL-17 and CRP in CSU.METHODS:
Concentrations of IL-17 in plasma and CRP in serum were measured in patients with CSU of varying severity and in the healthy subjects.RESULTS:
IL-17 and CRP concentrations were significantly higher in CSU patients as compared to the healthy subjects. In addition, there were significant differences in IL-17 and CRP concentrations between CSU patients with mild, moderate-severe symptoms and the healthy subjects. CRP did not correlate significantly with IL-17.CONCLUSIONS:
Increased circulating IL-17 concentration may represent an independent index of systemic inflammatory response in CSU, which is not related to increased CRP concentration.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Allergy Asthma Clin Immunol
Año:
2017
Tipo del documento:
Article
País de afiliación:
Polonia