Identification of a conformational heparin-recognition motif on the peptide hormone secretin: key role for cell surface binding.

Quittot, Noé; Nguyen, Phuong Trang; Nerée, Armelle Tchoumi; Lussier, Marc P; Bourgault, Steve

Quittot, Noé; Nguyen, Phuong Trang; Nerée, Armelle Tchoumi; Lussier, Marc P; Bourgault, Steve.

Afiliación

Quittot N; Department of Chemistry, Pharmaqam, University of Québec in Montreal, Montreal, QC, Canada H3C 3P8.
Nguyen PT; Quebec Network for Research on Protein Function, Engineering, and Applications, PROTEO, Québec, QC, Canada.
Nerée AT; Department of Chemistry, Pharmaqam, University of Québec in Montreal, Montreal, QC, Canada H3C 3P8.
Lussier MP; Quebec Network for Research on Protein Function, Engineering, and Applications, PROTEO, Québec, QC, Canada.
Bourgault S; Department of Chemistry, Pharmaqam, University of Québec in Montreal, Montreal, QC, Canada H3C 3P8.

Biochem J ; 474(13): 2249-2260, 2017 06 26.

Article en En | MEDLINE | ID: mdl-28536157

Asunto(s)

Membrana Celular/metabolismo; Glicosaminoglicanos/metabolismo; Heparina/metabolismo; Secretina/metabolismo; Heparina/química; Humanos; Conformación Molecular; Unión Proteica; Conformación Proteica; Secretina/química; Resonancia por Plasmón de Superficie

Palabras clave

glycosaminoglycans; heparin-binding motif; membranes; peptides

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Secretina / Heparina / Membrana Celular / Glicosaminoglicanos Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Biochem J Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido

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