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Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil.
Ishida, Kaoru; Ito, Chie; Ohmori, Yukimi; Kume, Kohei; Sato, Kei A; Koizumi, Yuka; Konta, Akari; Iwaya, Takeshi; Nukatsuka, Mamoru; Kobunai, Takashi; Takechi, Teiji; Nishizuka, Satoshi S.
Afiliación
  • Ishida K; Molecular Therapeutics Laboratory, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Iwate, 020-8505, Japan.
  • Ito C; Molecular Therapeutics Laboratory, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Iwate, 020-8505, Japan.
  • Ohmori Y; Molecular Therapeutics Laboratory, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Iwate, 020-8505, Japan.
  • Kume K; Molecular Therapeutics Laboratory, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Iwate, 020-8505, Japan.
  • Sato KA; Division of Biomedical Research and Development, Institute of Biomedical Science, Iwate Medical University, Morioka, Iwate, 020-8505, Japan.
  • Koizumi Y; Molecular Therapeutics Laboratory, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Iwate, 020-8505, Japan.
  • Konta A; Molecular Therapeutics Laboratory, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Iwate, 020-8505, Japan.
  • Iwaya T; Molecular Therapeutics Laboratory, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Iwate, 020-8505, Japan.
  • Nukatsuka M; Molecular Therapeutics Laboratory, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Iwate, 020-8505, Japan.
  • Kobunai T; Translational Research Laboratory, Taiho Pharmaceutical Co., Ltd., Tokushima, Tokushima, 771-0194, Japan.
  • Takechi T; Translational Research Laboratory, Taiho Pharmaceutical Co., Ltd., Tokushima, Tokushima, 771-0194, Japan.
  • Nishizuka SS; Translational Research Laboratory, Taiho Pharmaceutical Co., Ltd., Tokushima, Tokushima, 771-0194, Japan.
Sci Rep ; 7(1): 2262, 2017 05 23.
Article en En | MEDLINE | ID: mdl-28536445
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resistencia a Antineoplásicos / Fluorouracilo / Inhibidores de las Quinasa Fosfoinosítidos-3 / Antimetabolitos Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resistencia a Antineoplásicos / Fluorouracilo / Inhibidores de las Quinasa Fosfoinosítidos-3 / Antimetabolitos Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido