KFLC Index utility in multiple sclerosis diagnosis: Further confirmation.
J Neuroimmunol
; 309: 31-33, 2017 08 15.
Article
en En
| MEDLINE
| ID: mdl-28601282
ABSTRACT
The Multiple Sclerosis (MS) diagnosis is based on dissemination of focal lesions in time and space. The free light chains (FLCs) determination might be a sensitive alternative to oligoclonal bands assay. The study aim was to redefine sensitivity, specificity of the kFLC Index cut-off. We analyzed serum and cerebrospinal fluid of 176 patients, with different neurological disorders. We obtained a cut off of 12,3 for kFLC Index with a sensitivity and specificity of 93% and 100% respectively. Our data confirm that the kFLC Index is a valid tool in the diagnosis of MS.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cadenas Ligeras de Inmunoglobulina
/
Esclerosis Múltiple
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
J Neuroimmunol
Año:
2017
Tipo del documento:
Article
País de afiliación:
Italia