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Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway.
Jin, Huiling; Fujita, Takayuki; Jin, Meihua; Kurotani, Reiko; Namekata, Iyuki; Hamaguchi, Shogo; Hidaka, Yuko; Cai, Wenqian; Suita, Kenji; Ohnuki, Yoshiki; Mototani, Yasumasa; Shiozawa, Kouichi; Prajapati, Rajesh; Liang, Chen; Umemura, Masanari; Yokoyama, Utako; Sato, Motohiko; Tanaka, Hikaru; Okumura, Satoshi; Ishikawa, Yoshihiro.
Afiliación
  • Jin H; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.
  • Fujita T; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.
  • Jin M; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan; Department of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka 565-8565, Japan.
  • Kurotani R; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan; Department of Physiology, Biochemical Engineering, Faculty of Engineering, Yamagata University, Yamagata 992-8510, Japan.
  • Namekata I; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Chiba 274-8510, Japan.
  • Hamaguchi S; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Chiba 274-8510, Japan.
  • Hidaka Y; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.
  • Cai W; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.
  • Suita K; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan; Department of Physiology, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.
  • Ohnuki Y; Department of Physiology, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.
  • Mototani Y; Department of Physiology, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.
  • Shiozawa K; Department of Physiology, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan.
  • Prajapati R; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.
  • Liang C; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.
  • Umemura M; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.
  • Yokoyama U; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.
  • Sato M; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan; Department of Physiology, Aichi Medical University, Aichi 480-1195, Japan.
  • Tanaka H; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Chiba 274-8510, Japan.
  • Okumura S; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan; Department of Physiology, Tsurumi University School of Dental Medicine, Yokohama 230-8501, Japan. Electronic address: okumura-s@tsurumi-u.ac.jp.
  • Ishikawa Y; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan. Electronic address: yishikaw@yokohama-cu.ac.jp.
J Mol Cell Cardiol ; 108: 170-180, 2017 07.
Article en En | MEDLINE | ID: mdl-28629760
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Expresión Génica / Disfunción Ventricular / Factores de Intercambio de Guanina Nucleótido / Miocitos Cardíacos / Factores de Transcripción STAT / Quinasas Janus Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Mol Cell Cardiol Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Expresión Génica / Disfunción Ventricular / Factores de Intercambio de Guanina Nucleótido / Miocitos Cardíacos / Factores de Transcripción STAT / Quinasas Janus Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Mol Cell Cardiol Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido