Effect of resolution recovery using graph plots on regional cerebral blood flow in healthy volunteers.
Ann Nucl Med
; 31(7): 553-562, 2017 Aug.
Article
en En
| MEDLINE
| ID: mdl-28664319
ABSTRACT
PURPOSE:
We evaluated the effect of resolution recovery (RR) using graph plots on regional cerebral blood flow (rCBF) in brain perfusion single-photon emission computed tomography (SPECT) images derived from healthy volunteers and patients diagnosed with probable Alzheimer's disease.METHOD:
We acquired brain perfusion SPECT images with scatter correction (SC), computed tomography-based attenuation correction (CTAC), and RR from a three-dimensional brain phantom and from healthy volunteers. We then compared contrast-to-noise ratio, count density ratios, increase maps, and rCBF using statistical parametric mapping 8.RESULTS:
Regional brain counts were significantly increased from 20-24% with SC, CTAC, and RR compared with SC and CTAC. Mean CBF in healthy volunteers was 42.5 ± 5.4 mL/100 g/min. Average rCBF determined using SC, CTAC and RR increased 7.5, 2.0, and 3.7% at the thalamus, posterior cingulate, and whole brain, respectively, compared with SC and CTAC.CONCLUSION:
Resolution recovery caused variations in normal rCBF because counts increased in cerebral regions.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Procesamiento de Imagen Asistido por Computador
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Tomografía Computarizada de Emisión de Fotón Único
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Circulación Cerebrovascular
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Voluntarios Sanos
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Ann Nucl Med
Asunto de la revista:
MEDICINA NUCLEAR
Año:
2017
Tipo del documento:
Article
País de afiliación:
Japón