Polyamine Transport and Synthesis in Trichomonas vaginalis: Potential Therapeutic Targets.
Curr Pharm Des
; 23(23): 3359-3366, 2017.
Article
en En
| MEDLINE
| ID: mdl-28671057
ABSTRACT
Polyamines are essential for many biological processes in all organisms. Here we show a current landscape of studies and strategies implemented for the study of polyamine metabolism, as well as molecular aspects that implicate the role of key enzymes, transport proteins, inhibitors, and the study of novel molecules as potential therapeutic targets. This review focused on the synthesis, interconversion and function of these molecules in Trichomonas vaginalis, a common sexually transmitted parasite of humans.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Poliaminas
/
Trichomonas vaginalis
/
Sistemas de Liberación de Medicamentos
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Antiparasitarios
Límite:
Animals
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Female
/
Humans
Idioma:
En
Revista:
Curr Pharm Des
Asunto de la revista:
FARMACIA
Año:
2017
Tipo del documento:
Article
Pais de publicación:
AE
/
EMIRADOS ÁRABES UNIDOS
/
EMIRATOS ARABES UNIDOS
/
UNITED ARAB EMIRATES