Chloroquine efficacy for Plasmodium vivax in Myanmar in populations with high genetic diversity and moderate parasite gene flow.

Htun, Myo Win; Mon, Nan Cho Nwe; Aye, Khin Myo; Hlaing, Chan Myae; Kyaw, Myat Phone; Handayuni, Irene; Trimarsanto, Hidayat; Bustos, Dorina; Ringwald, Pascal; Price, Ric N; Auburn, Sarah; Thriemer, Kamala

Htun, Myo Win; Mon, Nan Cho Nwe; Aye, Khin Myo; Hlaing, Chan Myae; Kyaw, Myat Phone; Handayuni, Irene; Trimarsanto, Hidayat; Bustos, Dorina; Ringwald, Pascal; Price, Ric N; Auburn, Sarah; Thriemer, Kamala.

Afiliación

Htun MW; Department of Medical Research, Yangon, 11191, Myanmar.
Mon NCN; Department of Medical Research, Yangon, 11191, Myanmar.
Aye KM; Department of Medical Research, Yangon, 11191, Myanmar.
Hlaing CM; Department of Medical Research, Yangon, 11191, Myanmar.
Kyaw MP; Department of Medical Research, Yangon, 11191, Myanmar.
Handayuni I; Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, NT, 0810, Australia.
Trimarsanto H; Eijkman Institute for Molecular Biology, Jl. Diponegoro 69, Central Jakarta, 10430, Indonesia.
Bustos D; The Ministry of Research and Technology (RISTEK), Jakarta, Indonesia.
Ringwald P; Agency for Assessment and Application of Technology, Jl. MH Thamrin 8, Jakarta, 10340, Indonesia.
Price RN; World Health Organization, Country Office for Thailand, Ministry of Public Health, Nonthaburi, Thailand.
Auburn S; Global Malaria Programme, World Health Organization, 20 Avenue Appia, 1211, Geneva, 27, Switzerland.
Thriemer K; Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, NT, 0810, Australia.

Malar J ; 16(1): 281, 2017 07 10.

Article en En | MEDLINE | ID: mdl-28693552

Asunto(s)

Antimaláricos/farmacología; Cloroquina/farmacología; Flujo Génico; Variación Genética; Malaria Vivax/tratamiento farmacológico; Plasmodium vivax/efectos de los fármacos; Plasmodium vivax/genética; Adolescente; Adulto; Anciano; Anciano de 80 o más Años; Niño; Estudios Transversales; Variaciones en el Número de Copia de ADN; Femenino; Genotipo; Humanos; Masculino; Repeticiones de Microsatélite/genética; Persona de Mediana Edad; Proteínas Asociadas a Resistencia a Múltiples Medicamentos/genética; Mianmar; Proteínas Protozoarias/genética; Adulto Joven

Palabras clave

Chloroquine; Copy number; Diversity; Efficacy; Genotyping; Malaria; Myanmar; Plasmodium; Resistance; Transmission; Vivax; pvmdr1

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plasmodium vivax / Variación Genética / Cloroquina / Malaria Vivax / Flujo Génico / Antimaláricos Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Malar J Asunto de la revista: MEDICINA TROPICAL Año: 2017 Tipo del documento: Article País de afiliación: Myanmar Pais de publicación: Reino Unido

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