New Tools for Cryptosporidium Lead to New Hope for Cryptosporidiosis.
Trends Parasitol
; 33(9): 662-664, 2017 09.
Article
en En
| MEDLINE
| ID: mdl-28750950
ABSTRACT
The pyrazolopyridine KDU731 is a promising drug candidate for treatment of diarrhea caused by Cryptosporidium in young children in the resource-limited world. KDU731, a PI (4) kinase inhibitor, blocks Cryptosporidium infection in vitro and in vivo in immunocompromised mice and dramatically reduces oocyst shedding, diarrhea, and dehydration in neonatal calves.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pirazoles
/
Piridinas
/
Criptosporidiosis
/
Diarrea
Tipo de estudio:
Etiology_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Parasitol
Asunto de la revista:
PARASITOLOGIA
Año:
2017
Tipo del documento:
Article