Oncocytic papillary cystadenoma with prominent mucinous differentiation of parotid gland: A case report.
Pathol Res Pract
; 213(10): 1310-1314, 2017 Oct.
Article
en En
| MEDLINE
| ID: mdl-28756976
We describe the case of an oncocytic papillary cystadenoma with mucinous differentiation of the parotid gland in a 64-year-old male. Histologically, the tumor exhibited distinctive areas of intracystic papillary growth pattern with microcystic and macrocystic spaces containing mucinous secretions and small crystals. The cyst wall and papillary fronds were lined by oncocytic admixed with numerous mucocytes. Lymphoid tissue and invasive features were not identified. The tumor showed strong expression of CK7 and mammaglobin in oncocytes, and BRST-2 and MUC4 in mucocytes. p63, ER, PR, SOX10, DOG-1, and S100 stains were negative. No rearrangement of the MAML2 gene region or ETV6-NTRK3 fusion transcript was detected. The diagnosis of oncocytic papillary tumor with prominent mucinous differentiation is particularly problematic owing to the large number of potential mimics and should prompt consideration of appropriate molecular studies.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Parótida
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Diferenciación Celular
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Neoplasias Quísticas, Mucinosas y Serosas
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Cistoadenoma Papilar
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Células Oxífilas
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Pathol Res Pract
Año:
2017
Tipo del documento:
Article
Pais de publicación:
Alemania