Neuroprotective properties of anthocyanidin glycosides against H<sub>2</sub>O<sub>2</sub>-induced glial cell death are modulated by their different stability and antioxidant activity in vitro.

Ereminas, Gedas; Majiene, Daiva; Sidlauskas, Kastytis; Jakstas, Valdas; Ivanauskas, Liudas; Vaitiekaitis, Gintautas; Liobikas, Julius

Neuroprotective properties of anthocyanidin glycosides against H₂O₂-induced glial cell death are modulated by their different stability and antioxidant activity in vitro.

Ereminas, Gedas; Majiene, Daiva; Sidlauskas, Kastytis; Jakstas, Valdas; Ivanauskas, Liudas; Vaitiekaitis, Gintautas; Liobikas, Julius.

Afiliación

Ereminas G; Laboratory of Biochemistry, Neuroscience Institute, Lithuanian University of Health Sciences, Eiveniu str. 4 LT, 50161, Kaunas, Lithuania.
Majiene D; Laboratory of Biochemistry, Neuroscience Institute, Lithuanian University of Health Sciences, Eiveniu str. 4 LT, 50161, Kaunas, Lithuania.
Sidlauskas K; Laboratory of Biochemistry, Neuroscience Institute, Lithuanian University of Health Sciences, Eiveniu str. 4 LT, 50161, Kaunas, Lithuania.
Jakstas V; Department of Pharmacognosy, Faculty of Pharmacy, Lithuanian University of Health Sciences, Eiveniu str. 4, LT, 50161 Kaunas, Lithuania.
Ivanauskas L; Department of Analytical and Toxicological Chemistry, Faculty of Pharmacy, Lithuanian University of Health Sciences, Eiveniu str. 4, LT, 50161, Kaunas, Lithuania.
Vaitiekaitis G; Department of Physics, Mathematics and Biophysics, Faculty of Medicine, Lithuanian University of Health Sciences, Eiveniu str. 4, LT, 50161, Kaunas, Lithuania.
Liobikas J; Laboratory of Biochemistry, Neuroscience Institute, Lithuanian University of Health Sciences, Eiveniu str. 4 LT, 50161, Kaunas, Lithuania. Electronic address: julius.liobikas@lsmuni.lt.

Biomed Pharmacother ; 94: 188-196, 2017 Oct.

Article en En | MEDLINE | ID: mdl-28759756

Asunto(s)

Antocianinas/farmacología; Antioxidantes/farmacología; Glucósidos/farmacología; Peróxido de Hidrógeno/toxicidad; Neuroglía/efectos de los fármacos; Fármacos Neuroprotectores/farmacología; Estrés Oxidativo/efectos de los fármacos; Animales; Técnicas de Cultivo de Célula; Línea Celular; Supervivencia Celular/efectos de los fármacos; Estabilidad de Medicamentos; Neuroglía/metabolismo; Neuroglía/patología; Fosforilación Oxidativa; Ratas

Palabras clave

Anthocyanin; Cell death; Glial cell; Neuroprotection; Oxidative phosphorylation; Oxidative stress

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neuroglía / Estrés Oxidativo / Fármacos Neuroprotectores / Glucósidos / Peróxido de Hidrógeno / Antocianinas / Antioxidantes Límite: Animals Idioma: En Revista: Biomed Pharmacother Año: 2017 Tipo del documento: Article País de afiliación: Lituania Pais de publicación: Francia

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