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Improvement of Pharmacokinetic Profile of TRAIL via Trimer-Tag Enhances its Antitumor Activity in vivo.
Liu, Haipeng; Su, Danmei; Zhang, Jinlong; Ge, Shuaishuai; Li, Youwei; Wang, Fei; Gravel, Michel; Roulston, Anne; Song, Qin; Xu, Wei; Liang, Joshua G; Shore, Gordon; Wang, Xiaodong; Liang, Peng.
Afiliación
  • Liu H; Department of Biochemistry & Molecular Biology, College of Life Sciences, Sichuan University, Chengdu, China.
  • Su D; Department of Biochemistry & Molecular Biology, College of Life Sciences, Sichuan University, Chengdu, China.
  • Zhang J; Department of Biochemistry & Molecular Biology, College of Life Sciences, Sichuan University, Chengdu, China.
  • Ge S; Department of Biochemistry & Molecular Biology, College of Life Sciences, Sichuan University, Chengdu, China.
  • Li Y; Department of Biochemistry & Molecular Biology, College of Life Sciences, Sichuan University, Chengdu, China.
  • Wang F; Department of Biochemistry & Molecular Biology, College of Life Sciences, Sichuan University, Chengdu, China.
  • Gravel M; Laboratory for Therapeutic Development, Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal (QC), Canada.
  • Roulston A; Laboratory for Therapeutic Development, Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal (QC), Canada.
  • Song Q; Clover Biopharmaceuticals, Chengdu, China.
  • Xu W; Clover Biopharmaceuticals, Chengdu, China.
  • Liang JG; Clover Biopharmaceuticals, Chengdu, China.
  • Shore G; Laboratory for Therapeutic Development, Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal (QC), Canada.
  • Wang X; National Institute of Biological Sciences, Beijing, China.
  • Liang P; Department of Biochemistry & Molecular Biology, College of Life Sciences, Sichuan University, Chengdu, China. liang.peng@cloverbiopharma.com.
Sci Rep ; 7(1): 8953, 2017 08 21.
Article en En | MEDLINE | ID: mdl-28827692
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfopéptidos / Proteínas Recombinantes de Fusión / Procolágeno / Neoplasias del Colon / Ligando Inductor de Apoptosis Relacionado con TNF / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfopéptidos / Proteínas Recombinantes de Fusión / Procolágeno / Neoplasias del Colon / Ligando Inductor de Apoptosis Relacionado con TNF / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido