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Dysfunction of the MDM2/p53 axis is linked to premature aging.
Lessel, Davor; Wu, Danyi; Trujillo, Carlos; Ramezani, Thomas; Lessel, Ivana; Alwasiyah, Mohammad K; Saha, Bidisha; Hisama, Fuki M; Rading, Katrin; Goebel, Ingrid; Schütz, Petra; Speit, Günter; Högel, Josef; Thiele, Holger; Nürnberg, Gudrun; Nürnberg, Peter; Hammerschmidt, Matthias; Zhu, Yan; Tong, David R; Katz, Chen; Martin, George M; Oshima, Junko; Prives, Carol; Kubisch, Christian.
Afiliación
  • Lessel D; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Wu D; Department of Biological Sciences, Columbia University, New York, New York, USA.
  • Trujillo C; Genetics Unit, Dr. Erfan & Bagedo Hospital, Jeddah, Saudi Arabia.
  • Ramezani T; Institute of Developmental Biology, University of Cologne, Cologne, Germany.
  • Lessel I; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Alwasiyah MK; Aziziah Maternity and Children's Hospital, Ministry of Health, Jeddah, Saudi Arabia.
  • Saha B; Department of Pathology, University of Washington, Seattle, Washington, USA.
  • Hisama FM; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington, USA.
  • Rading K; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Goebel I; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Schütz P; Institute of Human Genetics, University of Ulm, Ulm, Germany.
  • Speit G; Institute of Human Genetics, University of Ulm, Ulm, Germany.
  • Högel J; Institute of Human Genetics, University of Ulm, Ulm, Germany.
  • Thiele H; Cologne Center for Genomics.
  • Nürnberg G; Cologne Center for Genomics.
  • Nürnberg P; Cologne Center for Genomics.
  • Hammerschmidt M; Center for Molecular Medicine Cologne, and.
  • Zhu Y; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany.
  • Tong DR; Institute of Developmental Biology, University of Cologne, Cologne, Germany.
  • Katz C; Center for Molecular Medicine Cologne, and.
  • Martin GM; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany.
  • Oshima J; Department of Biological Sciences, Columbia University, New York, New York, USA.
  • Prives C; Department of Biological Sciences, Columbia University, New York, New York, USA.
  • Kubisch C; Department of Biological Sciences, Columbia University, New York, New York, USA.
J Clin Invest ; 127(10): 3598-3608, 2017 Oct 02.
Article en En | MEDLINE | ID: mdl-28846075
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pez Cebra / Proteína p53 Supresora de Tumor / Mutación de Línea Germinal / Envejecimiento Prematuro / Proteínas de Pez Cebra / Proteínas Proto-Oncogénicas c-mdm2 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Clin Invest Año: 2017 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pez Cebra / Proteína p53 Supresora de Tumor / Mutación de Línea Germinal / Envejecimiento Prematuro / Proteínas de Pez Cebra / Proteínas Proto-Oncogénicas c-mdm2 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Clin Invest Año: 2017 Tipo del documento: Article País de afiliación: Alemania