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ß2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's disease.
Mittal, Shuchi; Bjørnevik, Kjetil; Im, Doo Soon; Flierl, Adrian; Dong, Xianjun; Locascio, Joseph J; Abo, Kristine M; Long, Elizabeth; Jin, Ming; Xu, Bing; Xiang, Yang K; Rochet, Jean-Christophe; Engeland, Anders; Rizzu, Patrizia; Heutink, Peter; Bartels, Tim; Selkoe, Dennis J; Caldarone, Barbara J; Glicksman, Marcie A; Khurana, Vikram; Schüle, Birgitt; Park, David S; Riise, Trond; Scherzer, Clemens R.
Afiliación
  • Mittal S; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Bjørnevik K; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Im DS; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Flierl A; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
  • Dong X; The Norwegian Multiple Sclerosis Competence Center, Department of Neurology, Haukeland University Hospital, Norway.
  • Locascio JJ; Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
  • Abo KM; The Parkinson's Institute and Clinical Center, Sunnyvale, CA 94085, USA.
  • Long E; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Jin M; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Xu B; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Xiang YK; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Rochet JC; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Engeland A; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Rizzu P; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Heutink P; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Bartels T; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Selkoe DJ; Department of Pharmacology, University of California at Davis, Davis, CA 95616, USA.
  • Caldarone BJ; Department of Pharmacology, University of California at Davis, Davis, CA 95616, USA.
  • Glicksman MA; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
  • Khurana V; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
  • Schüle B; Department of Pharmacoepidemiology, Norwegian Institute of Public Health, Oslo, Norway.
  • Park DS; German Center for Neurodegenerative Diseases (DZNE), Tübingen 72076, Germany.
  • Riise T; German Center for Neurodegenerative Diseases (DZNE), Tübingen 72076, Germany.
  • Scherzer CR; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Science ; 357(6354): 891-898, 2017 09 01.
Article en En | MEDLINE | ID: mdl-28860381

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Regulación de la Expresión Génica / Receptores Adrenérgicos beta 2 / Alfa-Sinucleína Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans País/Región como asunto: Europa Idioma: En Revista: Science Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Regulación de la Expresión Génica / Receptores Adrenérgicos beta 2 / Alfa-Sinucleína Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans País/Región como asunto: Europa Idioma: En Revista: Science Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos