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The G-quadruplex DNA stabilizing drug pyridostatin promotes DNA damage and downregulates transcription of Brca1 in neurons.
Moruno-Manchon, Jose F; Koellhoffer, Edward C; Gopakumar, Jayakrishnan; Hambarde, Shashank; Kim, Nayun; McCullough, Louise D; Tsvetkov, Andrey S.
Afiliación
  • Moruno-Manchon JF; Department of Neurobiology and Anatomy, the University of Texas McGovern Medical School at Houston, TX 77030, USA.
  • Koellhoffer EC; Department of Neurology, the University of Texas McGovern Medical School at Houston, TX 77030, USA.
  • Gopakumar J; Summer Research Program at the University of Texas McGovern Medical School at Houston, TX 77030, USA.
  • Hambarde S; Department of Microbiology and Molecular Genetics, the University of Texas McGovern Medical School at Houston, TX 77030, USA.
  • Kim N; Department of Microbiology and Molecular Genetics, the University of Texas McGovern Medical School at Houston, TX 77030, USA.
  • McCullough LD; The University of Texas Graduate School of Biomedical Sciences, Houston, TX 77030, USA.
  • Tsvetkov AS; Department of Neurology, the University of Texas McGovern Medical School at Houston, TX 77030, USA.
Aging (Albany NY) ; 9(9): 1957-1970, 2017 09 12.
Article en En | MEDLINE | ID: mdl-28904242
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Picolínicos / Transcripción Genética / Daño del ADN / Proteína BRCA1 / Aminoquinolinas / Neuronas Límite: Animals Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Picolínicos / Transcripción Genética / Daño del ADN / Proteína BRCA1 / Aminoquinolinas / Neuronas Límite: Animals Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos