Direct coupling of the HER4 intracellular domain (4ICD) and STAT5A signaling is required to induce mammary epithelial cell differentiation.
Biochem Biophys Rep
; 7: 323-327, 2016 Sep.
Article
en En
| MEDLINE
| ID: mdl-28955922
4ICD, HER4 intracellular domain; ATCC, American type culture collection; EGF, epidermal growth factor; EGFP, enhanced green fluorescent protein; EGFR, epidermal growth factor family; EGFR-family; ERα, estrogen receptor alpha; FBS, fetal bovine serum; Gene expression; HEK, human embryonic kidney; HER4/ERBB4; HRGα, heregulin alpha; HRGα1, heregulin beta 1; Mammary epithelial differentiation; NLS, nuclear localization signal; PCR, polymerase chain reaction; PI3K, phosphoinositide 3-kinase; RIP, regulated intramembrane cleavage; RT, reverse transcription; RTK, receptor tyrosine kinase; SH2, src homology 2; STAT5A; STAT5A, signal transducer and activator of transcription 5A; TACE, tumor necrosis factor-α-converting enzyme; Transactivation; WAP, whey acidic protein; YAP, yes-associated protein
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Biochem Biophys Rep
Año:
2016
Tipo del documento:
Article
País de afiliación:
Estados Unidos