Age at menarche and the risk of operative delivery.
J Matern Fetal Neonatal Med
; 32(3): 411-418, 2019 Feb.
Article
en En
| MEDLINE
| ID: mdl-28958167
ABSTRACT
OBJECTIVES:
We sought to evaluate the impact of later menarche on the risk of operative delivery. POPULATION We studied 38,069 eligible women (first labors at term with a singleton infant in a cephalic presentation) from the Norwegian Mothers and Child Cohort Study. The main exposures were the age at menarche and the duration of the interval between menarche and the first birth.METHODS:
Poisson's regression with a robust variance estimator. MAIN OUTCOMEMEASURES:
Operative delivery, defined as emergency cesarean or assisted vaginal delivery (ventouse extraction or forceps).RESULTS:
A 5 year increase in age at menarche was associated with a reduced risk of operative delivery (risk ratio [RR] 0.84, 95%CI 0.78, 0.89; p < .001). Adjustment for the age at first birth slightly strengthened the association (RR 0.79, 95%CI 0.74, 0.84; p < .001). However, the association was lost following adjustment for the menarche to birth interval (RR 0.99, 95%CI 0.93, 1.06; p = .81). A 5 years increase in menarche to birth interval was associated with an increased risk of operative delivery (RR 1.26, 95%CI 1.23, 1.28; p < .001). This was not materially affected by adjustment for an extensive series of maternal characteristics (RR 1.23, 95%CI 1.20, 1.25; p < .001).CONCLUSIONS:
Later menarche reduces the risk of an operative first birth through shortening the menarche to birth interval. This observation is consistent with the hypothesis that the pattern and/or duration of prepregnancy exposure of the uterus to estrogen and progesterone contributes to uterine aging.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Menarquia
/
Parto Obstétrico
/
Complicaciones del Trabajo de Parto
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
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Male
/
Newborn
/
Pregnancy
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Matern Fetal Neonatal Med
Asunto de la revista:
OBSTETRICIA
/
PERINATOLOGIA
Año:
2019
Tipo del documento:
Article
País de afiliación:
Reino Unido