BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.

Zhao, Weixing; Steinfeld, Justin B; Liang, Fengshan; Chen, Xiaoyong; Maranon, David G; Jian Ma, Chu; Kwon, Youngho; Rao, Timsi; Wang, Weibin; Sheng, Chen; Song, Xuemei; Deng, Yanhong; Jimenez-Sainz, Judit; Lu, Lucy; Jensen, Ryan B; Xiong, Yong; Kupfer, Gary M; Wiese, Claudia; Greene, Eric C; Sung, Patrick

Zhao, Weixing; Steinfeld, Justin B; Liang, Fengshan; Chen, Xiaoyong; Maranon, David G; Jian Ma, Chu; Kwon, Youngho; Rao, Timsi; Wang, Weibin; Sheng, Chen; Song, Xuemei; Deng, Yanhong; Jimenez-Sainz, Judit; Lu, Lucy; Jensen, Ryan B; Xiong, Yong; Kupfer, Gary M; Wiese, Claudia; Greene, Eric C; Sung, Patrick.

Afiliación

Zhao W; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Steinfeld JB; Department of Biochemistry & Molecular Biophysics, Columbia University, New York, New York 10032, USA.
Liang F; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Chen X; Section of Hematology-Oncology, Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Maranon DG; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Jian Ma C; Section of Hematology-Oncology, Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Kwon Y; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Rao T; Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523, USA.
Wang W; Department of Biochemistry & Molecular Biophysics, Columbia University, New York, New York 10032, USA.
Sheng C; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Song X; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Deng Y; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Jimenez-Sainz J; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Lu L; Yale Center for Analytical Sciences, Yale School of Public Health, New Haven, Connecticut, USA.
Jensen RB; Yale Center for Analytical Sciences, Yale School of Public Health, New Haven, Connecticut, USA.
Xiong Y; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Kupfer GM; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Wiese C; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Greene EC; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Sung P; Section of Hematology-Oncology, Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

Nature ; 550(7676): 360-365, 2017 10 19.

Article en En | MEDLINE | ID: mdl-28976962

Asunto(s)

Proteína BRCA1/metabolismo; Emparejamiento Base; Emparejamiento Cromosómico; Recombinasa Rad51/metabolismo; Reparación del ADN por Recombinación; Homología de Secuencia de Ácido Nucleico; Proteínas Supresoras de Tumor/metabolismo; Ubiquitina-Proteína Ligasas/metabolismo; Secuencia de Aminoácidos; Proteína BRCA1/genética; Proteína BRCA2/genética; Proteína BRCA2/metabolismo; Proteína del Grupo de Complementación N de la Anemia de Fanconi/genética; Proteína del Grupo de Complementación N de la Anemia de Fanconi/metabolismo; Genes BRCA1; Genes BRCA2; Humanos; Complejos Multiproteicos/química; Complejos Multiproteicos/genética; Complejos Multiproteicos/metabolismo; Mutación; Unión Proteica; Recombinasa Rad51/genética; Reparación del ADN por Recombinación/genética; Moldes Genéticos; Proteínas Supresoras de Tumor/química; Proteínas Supresoras de Tumor/genética; Ubiquitina-Proteína Ligasas/química; Ubiquitina-Proteína Ligasas/genética

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Homología de Secuencia de Ácido Nucleico / Proteína BRCA1 / Emparejamiento Base / Proteínas Supresoras de Tumor / Emparejamiento Cromosómico / Ubiquitina-Proteína Ligasas / Recombinasa Rad51 / Reparación del ADN por Recombinación Límite: Humans Idioma: En Revista: Nature Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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