A tracking algorithm for cell motility assays in CMOS systems.
Annu Int Conf IEEE Eng Med Biol Soc
; 2017: 837-840, 2017 Jul.
Article
en En
| MEDLINE
| ID: mdl-29060002
ABSTRACT
This work proposes a method for the study and real-time monitoring of a single cell on a 2D electrode matrix, of great interest in cell motility assays and in the characterization of cancer cell metastasis. A CMOS system proposal for cell location based on occupation maps data generated from Electrical Cell-substrate Impedance Spectroscopy (ECIS) has been developed. From experimental assays data, an algorithm based on the analysis of the eight nearest neighbours has been implemented to find the cell center of mass. The path followed by a cell, proposing a Brownian route, has been simulated with the proposed algorithm. The presented results give an accuracy over 95% in the determination of the coordinates (x, y) from the expected cell center of mass.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ensayos de Migración Celular
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Annu Int Conf IEEE Eng Med Biol Soc
Año:
2017
Tipo del documento:
Article