Isolation and structural identification of a novel minoxidil analogue in an illegal dietary supplement: triaminodil.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
; 35(1): 2-9, 2018 Jan.
Article
en En
| MEDLINE
| ID: mdl-29067865
ABSTRACT
A new minoxidil analogue was detected in an illegal dietary supplement advertised as a hair-growth treatment. The analogue was identified using ultra-performance liquid chromatography (UPLC), high-resolution mass spectrometry (LC-HR-MS) and nuclear magnetic resonance (NMR) spectroscopy. The compound was structurally elucidated as a minoxidil analogue in which the piperidinyl group of minoxidil was replaced with a pyrrolidinyl group corresponding to a molecular formula of C8H13N5O. The new analogue has been named triaminodil. As this is the first report of the compound, there are no chemical, toxicology or pharmacological data available.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Contaminación de Medicamentos
/
Suplementos Dietéticos
/
Minoxidil
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
Asunto de la revista:
CIENCIAS DA NUTRICAO
Año:
2018
Tipo del documento:
Article