The superiority of combination beclomethasone and salbutamol over standard dosing of salbutamol in the treatment of chronic asthma.
Ann Allergy
; 62(1): 63-6, 1989 Jan.
Article
en En
| MEDLINE
| ID: mdl-2912326
ABSTRACT
We studied the clinical effect of a combination aerosol containing salbutamol and beclomethasone dipropionate in comparison to doubling the standard dose of salbutamol from an inhaler. Fifty-seven patients completed the double-blind, crossover study. They were treated with either an aerosol of 100 micrograms beclomethasone dipropionate and 200 micrograms salbutamol or 400 micrograms salbutamol alone. Both regimens were administered four times a day for 4 weeks. The patients showed significant improvement in FEV1, PEFR, and symptom scores after treatment with beclomethasone dipropionate and salbutamol compared with pre-trial values and with treatment with double the dose of salbutamol. The patients demonstrated a clear preference for treatment with the combination of beclomethasone dipropionate and salbutamol. Regular treatment with beclomethasone dipropionate in addition to salbutamol as a combination inhaler provides much better control of asthma than merely increasing the dose of salbutamol in those patients poorly controlled on standard doses of inhaled bronchodilators.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Asma
/
Beclometasona
/
Albuterol
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Evaluation_studies
Límite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Ann Allergy
Año:
1989
Tipo del documento:
Article
País de afiliación:
Finlandia