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[Novelties in the treatment of pediatric immune thrombocytopenia - 2017]. / Újdonságok a gyermekkori immunthrombocytopenia kezelésében ­ 2017.
Kovács, Gábor; Kiss, Csongor.
Afiliación
  • Kovács G; II. Gyermekgyógyászati Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Tuzoltó u. 7-9., 1094.
  • Kiss C; Gyermekgyógyászati Klinika, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen.
Orv Hetil ; 158(48): 1891-1896, 2017 Dec.
Article en Hu | MEDLINE | ID: mdl-29172661
Immune thrombocitopenia in children is a very variable disease. International recommendations give therapeutic possibilities without strong protocols. In 2011, a therapeutic algorithm was published based on Hungarian practice. Recently, new innovative drugs have been available even in Hungary, so there is a need for modification of the therapeutic protocols. In this summary we give an overview about the current up-to-date management. In infancy and in childhood, high-dose immunglobulin treatment is recommended henceforward. In older children an alternative can be steroid therapy (pulses or long-term low-dose treatment). In resistant cases, a new thrombopoetin receptor stimulant, eltrombopag can be administered. This drug is registered in Hungary, and can very effectively influence the prognosis. Splenectomy is very rare nowadays in children. Immune thrombocytopenia is an unpredictable disease. Cure rate is about 70-80% of the cases, but management of the patients needs special care and specialist. Orv Hetil. 2017; 158(48): 1891-1896.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Esteroides / Benzoatos / Púrpura Trombocitopénica Idiopática / Inmunoglobulinas Intravenosas / Administración del Tratamiento Farmacológico / Hidrazinas Tipo de estudio: Guideline / Prognostic_studies Límite: Adolescent / Child / Child, preschool / Humans / Infant / Newborn Idioma: Hu Revista: Orv Hetil Año: 2017 Tipo del documento: Article Pais de publicación: Hungria

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Esteroides / Benzoatos / Púrpura Trombocitopénica Idiopática / Inmunoglobulinas Intravenosas / Administración del Tratamiento Farmacológico / Hidrazinas Tipo de estudio: Guideline / Prognostic_studies Límite: Adolescent / Child / Child, preschool / Humans / Infant / Newborn Idioma: Hu Revista: Orv Hetil Año: 2017 Tipo del documento: Article Pais de publicación: Hungria