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Quenching protein dynamics interferes with HIV capsid maturation.
Wang, Mingzhang; Quinn, Caitlin M; Perilla, Juan R; Zhang, Huilan; Shirra, Randall; Hou, Guangjin; Byeon, In-Ja; Suiter, Christopher L; Ablan, Sherimay; Urano, Emiko; Nitz, Theodore J; Aiken, Christopher; Freed, Eric O; Zhang, Peijun; Schulten, Klaus; Gronenborn, Angela M; Polenova, Tatyana.
Afiliación
  • Wang M; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
  • Quinn CM; Pittsburgh Center for HIV Protein Interactions, University of Pittsburgh School of Medicine, 1051 Biomedical Science Tower 3, 3501 Fifth Ave., Pittsburgh, PA, 15261, USA.
  • Perilla JR; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
  • Zhang H; Pittsburgh Center for HIV Protein Interactions, University of Pittsburgh School of Medicine, 1051 Biomedical Science Tower 3, 3501 Fifth Ave., Pittsburgh, PA, 15261, USA.
  • Shirra R; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA. jperilla@udel.edu.
  • Hou G; University of Illinois, Theoretical and Computational Biophysics Group, Urbana, IL, 61801, USA. jperilla@udel.edu.
  • Byeon IJ; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
  • Suiter CL; Pittsburgh Center for HIV Protein Interactions, University of Pittsburgh School of Medicine, 1051 Biomedical Science Tower 3, 3501 Fifth Ave., Pittsburgh, PA, 15261, USA.
  • Ablan S; Pittsburgh Center for HIV Protein Interactions, University of Pittsburgh School of Medicine, 1051 Biomedical Science Tower 3, 3501 Fifth Ave., Pittsburgh, PA, 15261, USA.
  • Urano E; Department of Structural Biology, University of Pittsburgh School of Medicine, 3501 Fifth Ave., Pittsburgh, PA, 15261, USA.
  • Nitz TJ; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
  • Aiken C; Pittsburgh Center for HIV Protein Interactions, University of Pittsburgh School of Medicine, 1051 Biomedical Science Tower 3, 3501 Fifth Ave., Pittsburgh, PA, 15261, USA.
  • Freed EO; Pittsburgh Center for HIV Protein Interactions, University of Pittsburgh School of Medicine, 1051 Biomedical Science Tower 3, 3501 Fifth Ave., Pittsburgh, PA, 15261, USA.
  • Zhang P; Department of Structural Biology, University of Pittsburgh School of Medicine, 3501 Fifth Ave., Pittsburgh, PA, 15261, USA.
  • Schulten K; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
  • Gronenborn AM; Pittsburgh Center for HIV Protein Interactions, University of Pittsburgh School of Medicine, 1051 Biomedical Science Tower 3, 3501 Fifth Ave., Pittsburgh, PA, 15261, USA.
  • Polenova T; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA.
Nat Commun ; 8(1): 1779, 2017 11 24.
Article en En | MEDLINE | ID: mdl-29176596
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Cápside / VIH-1 / Proteínas de la Cápside Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Cápside / VIH-1 / Proteínas de la Cápside Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido