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Decrease in toe pinch force in male type 2 diabetic patients with diabetic nephropathy.
Kataoka, Hiroaki; Miyatake, Nobuyuki; Kitayama, Naomi; Murao, Satoshi; Tanaka, Satoshi.
Afiliación
  • Kataoka H; Rehabilitation Center, KKR Takamatsu Hospital, 4-18, Tenjinmae, Takamatsu-city, Kagawa, 760-0018, Japan. h.kataoka59@gmail.com.
  • Miyatake N; Department of Hygiene, Faculty of Medicine, Kagawa University, Kagawa, Japan. h.kataoka59@gmail.com.
  • Kitayama N; Department of Hygiene, Faculty of Medicine, Kagawa University, Kagawa, Japan.
  • Murao S; Rehabilitation Center, KKR Takamatsu Hospital, 4-18, Tenjinmae, Takamatsu-city, Kagawa, 760-0018, Japan.
  • Tanaka S; Department of Diabetes and Endocrinology, KKR Takamatsu Hospital, Kagawa, Japan.
Clin Exp Nephrol ; 22(3): 647-652, 2018 Jun.
Article en En | MEDLINE | ID: mdl-29181659
BACKGROUND: The purpose of this cross-sectional study was to investigate the toe pinch force (TPF) of type 2 diabetic patients with diabetic nephropathy by disease stage, and to clarify the factors affecting the TPF. METHODS: Seventy-four men with diabetic nephropathy (age: 62.7 ± 8.9 years, duration of diabetes: 14.2 ± 8.6 years) were enrolled. According to the staging of diabetic nephropathy, TPF and knee extension force (KEF) were compared among three groups: normoalbuminuria, microalbuminuria, and overt nephropathy. In addition, we investigated factors influencing TPF and KEF by performing multiple regression analysis. RESULTS: Normoalbuminuria group, microalbuminuria group, and overt nephropathy group included 26, 25, and 23 patients, respectively. The TPF of the overt nephropathy group (3.15 ± 0.75 kg) was significantly lower than that of the normoalbuminuria (4.2 ± 0.7 kg, p < 0.001) and microalbuminuria groups (3.65 ± 0.81 kg, p = 0.022). The KEF of the overt nephropathy group (37.1 ± 8.3 kgf) was significantly lower than that of the normoalbuminuria group (44.8 ± 8.3 kgf, p = 0.010). Multiple regression analysis revealed that diabetic polyneuropathy (DPN) and diabetic nephropathy were determinant factors of the TPF; and age, body mass index, and diabetic nephropathy were determinant factors of the KEF. CONCLUSION: We found in male patients with diabetic nephropathy, the TPF and KEF decreased with progression of diabetic nephropathy. Furthermore, our findings suggest diabetic nephropathy and DPN are critically involved in the reduction of TPF and KEF.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Nefropatías Diabéticas / Fuerza Muscular Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Aged / Humans / Male / Middle aged Idioma: En Revista: Clin Exp Nephrol Asunto de la revista: NEFROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Nefropatías Diabéticas / Fuerza Muscular Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Aged / Humans / Male / Middle aged Idioma: En Revista: Clin Exp Nephrol Asunto de la revista: NEFROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón