New Pharmacological Opportunities for Betulinic Acid.
Planta Med
; 84(1): 8-19, 2018 Jan.
Article
en En
| MEDLINE
| ID: mdl-29202513
ABSTRACT
Betulinic acid is a naturally occurring pentacyclic lupane-type triterpenoid usually isolated from birch trees, but present in many other botanical sources. It is found in different plant organs, both as a free aglycon and as glycosyl derivatives. A wide range of pharmacological activities has been described for this triterpenoid, including antiviral and antitumor effects. In addition, several other interesting properties have been identified in the fields of immunity and metabolism, namely antidiabetic, antihyperlipidemic, and anti-inflammatory activities. Taken together, these latter three properties make betulinic acid a highly interesting prospect for treating metabolic syndrome. The present review focuses on the therapeutic potential of this agent, along with several of its semisynthetic derivatives, which could open new frontiers in the use of natural product-based medicines.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Triterpenos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Planta Med
Año:
2018
Tipo del documento:
Article
País de afiliación:
España