Molecular dynamics simulations suggest changes in electrostatic interactions as a potential mechanism through which serine phosphorylation inhibits DNA Polymerase ß's activity.

Homouz, Dirar; Joyce-Tan, Kwee Hong; Shahir Shamsir, Mohd; Moustafa, Ibrahim M; Idriss, Haitham

Homouz, Dirar; Joyce-Tan, Kwee Hong; Shahir Shamsir, Mohd; Moustafa, Ibrahim M; Idriss, Haitham.

Afiliación

Homouz D; Department of Physics, Khalifa University of Science and Technology, P.O. Box 127788, Abu Dhabi, United Arab Emirates; Department of Physics, University of Houston, Houston, TX, USA; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.
Joyce-Tan KH; Faculty of Bioscience and Bioengineering, Universiti Teknologi Malaysia, Johor, Malaysia.
Shahir Shamsir M; Faculty of Bioscience and Bioengineering, Universiti Teknologi Malaysia, Johor, Malaysia.
Moustafa IM; Department of Chemistry, Bowdoin College, ME, USA.
Idriss H; Department of Biology and Biochemistry, Birzeit University, Palestine. Electronic address: hidriss@birzeit.edu.

J Mol Graph Model ; 79: 192, 2018 01.

Article en En | MEDLINE | ID: mdl-29223917

Palabras clave

DNA polymerase beta; DNA repair; Molecular dynamics; Phosphorylation; Protein kinase C

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Mol Graph Model Asunto de la revista: BIOLOGIA MOLECULAR Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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