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Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.
Hoffman, Gabriel E; Hartley, Brigham J; Flaherty, Erin; Ladran, Ian; Gochman, Peter; Ruderfer, Douglas M; Stahl, Eli A; Rapoport, Judith; Sklar, Pamela; Brennand, Kristen J.
Afiliación
  • Hoffman GE; Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. gabriel.hoffman@mssm.edu.
  • Hartley BJ; Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. gabriel.hoffman@mssm.edu.
  • Flaherty E; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Ladran I; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Gochman P; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Ruderfer DM; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Stahl EA; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Rapoport J; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Sklar P; Childhood Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Brennand KJ; Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Nat Commun ; 8(1): 2225, 2017 12 20.
Article en En | MEDLINE | ID: mdl-29263384
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia / Encéfalo / ARN Mensajero / Células Madre Pluripotentes Inducidas / Células-Madre Neurales / Neuronas Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia / Encéfalo / ARN Mensajero / Células Madre Pluripotentes Inducidas / Células-Madre Neurales / Neuronas Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido