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Bisphenol A induces DSB-ATM-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts.
Mahemuti, Laziyan; Chen, Qixuan; Coughlan, Melanie C; Qiao, Cunye; Chepelev, Nikolai L; Florian, Maria; Dong, Dillon; Woodworth, Robert G; Yan, Jin; Cao, Xu-Liang; Scoggan, Kylie A; Jin, Xiaolei; Willmore, William G.
Afiliación
  • Mahemuti L; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, HPFB, Health Canada, PL2202D, 251 Sir Frederick Banting Drive Way, Ottawa, ON, K1A 0K9, Canada.
  • Chen Q; Departments of Biology and Chemistry, Institute of Biochemistry, Carleton University, Ottawa, ON, Canada.
  • Coughlan MC; Nutrition Research Division, Bureau of Nutrition Sciences, Food Directorate, HPFB, Health Canada, Ottawa, ON, Canada.
  • Qiao C; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, HPFB, Health Canada, PL2202D, 251 Sir Frederick Banting Drive Way, Ottawa, ON, K1A 0K9, Canada.
  • Chepelev NL; Biostatistics and Modeling Division, Bureau of Food Surveillance and Science Integration, Food Directorate, HPFB, Health Canada, Ottawa, ON, Canada.
  • Florian M; Departments of Biology and Chemistry, Institute of Biochemistry, Carleton University, Ottawa, ON, Canada.
  • Dong D; Mechanistic Studies Division, Environmental Health Science and Research Bureau, Environmental and Radiation Health Sciences Directorate, HECSB, Health Canada, Ottawa, ON, Canada.
  • Woodworth RG; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, HPFB, Health Canada, PL2202D, 251 Sir Frederick Banting Drive Way, Ottawa, ON, K1A 0K9, Canada.
  • Yan J; Departments of Biology and Chemistry, Institute of Biochemistry, Carleton University, Ottawa, ON, Canada.
  • Cao XL; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, HPFB, Health Canada, PL2202D, 251 Sir Frederick Banting Drive Way, Ottawa, ON, K1A 0K9, Canada.
  • Scoggan KA; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, HPFB, Health Canada, PL2202D, 251 Sir Frederick Banting Drive Way, Ottawa, ON, K1A 0K9, Canada.
  • Jin X; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, HPFB, Health Canada, PL2202D, 251 Sir Frederick Banting Drive Way, Ottawa, ON, K1A 0K9, Canada.
  • Willmore WG; Food Research Division, Bureau of Chemical Safety, Food Directorate, HPFB, Health Canada, Ottawa, ON, Canada.
Arch Toxicol ; 92(4): 1453-1469, 2018 Apr.
Article en En | MEDLINE | ID: mdl-29275510
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenoles / Compuestos de Bencidrilo / Proteína p53 Supresora de Tumor / Contaminantes Ocupacionales del Aire / Estradiol / Factor 2 Relacionado con NF-E2 / Citocromo P-450 CYP1B1 / 17-Hidroxiesteroide Deshidrogenasas / Pulmón Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Arch Toxicol Año: 2018 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenoles / Compuestos de Bencidrilo / Proteína p53 Supresora de Tumor / Contaminantes Ocupacionales del Aire / Estradiol / Factor 2 Relacionado con NF-E2 / Citocromo P-450 CYP1B1 / 17-Hidroxiesteroide Deshidrogenasas / Pulmón Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Arch Toxicol Año: 2018 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Alemania