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Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic-Industry Partnership.
Mo, Charlie Y; Culyba, Matthew J; Selwood, Trevor; Kubiak, Jeffrey M; Hostetler, Zachary M; Jurewicz, Anthony J; Keller, Paul M; Pope, Andrew J; Quinn, Amy; Schneck, Jessica; Widdowson, Katherine L; Kohli, Rahul M.
Afiliación
  • Mo CY; Department of Medicine, Department of Biochemistry and Biophysics , University of Pennsylvania , 3610 Hamilton Walk , Philadelphia , Pennsylvania 19104 , United States.
  • Culyba MJ; Department of Medicine, Department of Biochemistry and Biophysics , University of Pennsylvania , 3610 Hamilton Walk , Philadelphia , Pennsylvania 19104 , United States.
  • Selwood T; Department of Medicine, Department of Biochemistry and Biophysics , University of Pennsylvania , 3610 Hamilton Walk , Philadelphia , Pennsylvania 19104 , United States.
  • Kubiak JM; Department of Medicine, Department of Biochemistry and Biophysics , University of Pennsylvania , 3610 Hamilton Walk , Philadelphia , Pennsylvania 19104 , United States.
  • Hostetler ZM; Department of Medicine, Department of Biochemistry and Biophysics , University of Pennsylvania , 3610 Hamilton Walk , Philadelphia , Pennsylvania 19104 , United States.
  • Jurewicz AJ; Screening, Profiling, and Mechanistic Biology , GlaxoSmithKline , 1250 S. Collegeville Road , Collegeville , Pennsylvania 19426 , United States.
  • Keller PM; Screening, Profiling, and Mechanistic Biology , GlaxoSmithKline , 1250 S. Collegeville Road , Collegeville , Pennsylvania 19426 , United States.
  • Pope AJ; Discovery Partnerships with Academia , GlaxoSmithKline , 1250 S. Collegeville Road , Collegeville , Pennsylvania 19426 , United States.
  • Quinn A; Screening, Profiling, and Mechanistic Biology , GlaxoSmithKline , 1250 S. Collegeville Road , Collegeville , Pennsylvania 19426 , United States.
  • Schneck J; Screening, Profiling, and Mechanistic Biology , GlaxoSmithKline , 1250 S. Collegeville Road , Collegeville , Pennsylvania 19426 , United States.
  • Widdowson KL; Discovery Partnerships with Academia , GlaxoSmithKline , 1250 S. Collegeville Road , Collegeville , Pennsylvania 19426 , United States.
  • Kohli RM; Department of Medicine, Department of Biochemistry and Biophysics , University of Pennsylvania , 3610 Hamilton Walk , Philadelphia , Pennsylvania 19104 , United States.
ACS Infect Dis ; 4(3): 349-359, 2018 03 09.
Article en En | MEDLINE | ID: mdl-29275629

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacterias / Proteínas Bacterianas / Respuesta SOS en Genética / Serina Endopeptidasas / Colaboración Intersectorial / Proteolisis / Antibacterianos Tipo de estudio: Observational_studies / Prognostic_studies Idioma: En Revista: ACS Infect Dis Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacterias / Proteínas Bacterianas / Respuesta SOS en Genética / Serina Endopeptidasas / Colaboración Intersectorial / Proteolisis / Antibacterianos Tipo de estudio: Observational_studies / Prognostic_studies Idioma: En Revista: ACS Infect Dis Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos