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Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.
Duarte, Delfim; Hawkins, Edwin D; Akinduro, Olufolake; Ang, Heather; De Filippo, Katia; Kong, Isabella Y; Haltalli, Myriam; Ruivo, Nicola; Straszkowski, Lenny; Vervoort, Stephin J; McLean, Catriona; Weber, Tom S; Khorshed, Reema; Pirillo, Chiara; Wei, Andrew; Ramasamy, Saravana K; Kusumbe, Anjali P; Duffy, Ken; Adams, Ralf H; Purton, Louise E; Carlin, Leo M; Lo Celso, Cristina.
Afiliación
  • Duarte D; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ London, UK; The Francis Crick Institute, WC2A 3LY London, UK. Electronic address: delfimd@med.up.pt.
  • Hawkins ED; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ London, UK; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3010, Australia.
  • Akinduro O; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ London, UK.
  • Ang H; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ London, UK.
  • De Filippo K; Inflammation, Repair and Development, National Heart and Lung Institute, Imperial College London, SW7 2AZ London, UK.
  • Kong IY; The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3010, Australia.
  • Haltalli M; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ London, UK.
  • Ruivo N; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ London, UK.
  • Straszkowski L; Stem Cell Regulation Unit, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
  • Vervoort SJ; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
  • McLean C; Department of Haematology, Alfred Hospital, Melbourne, VIC 3004, Australia.
  • Weber TS; Hamilton Institute, Maynooth University, Maynooth, Ireland.
  • Khorshed R; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ London, UK.
  • Pirillo C; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ London, UK.
  • Wei A; Department of Haematology, Alfred Hospital, Melbourne, VIC 3004, Australia.
  • Ramasamy SK; Institute of Clinical Sciences, Imperial College London, W12 0NN London, UK.
  • Kusumbe AP; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Headington, Oxford OX3 7FY, UK.
  • Duffy K; Hamilton Institute, Maynooth University, Maynooth, Ireland.
  • Adams RH; Max Planck Institute for Molecular Biomedicine, Department of Tissue Morphogenesis, 48149 Munster, Germany; University of Münster, Faculty of Medicine, 48149 Munster, Germany.
  • Purton LE; Stem Cell Regulation Unit, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia; Department of Medicine, The University of Melbourne, Fitzroy, VIC 3065, Australia.
  • Carlin LM; Inflammation, Repair and Development, National Heart and Lung Institute, Imperial College London, SW7 2AZ London, UK; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
  • Lo Celso C; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, SW7 2AZ London, UK; The Francis Crick Institute, WC2A 3LY London, UK. Electronic address: c.lo-celso@imperial.ac.uk.
Cell Stem Cell ; 22(1): 64-77.e6, 2018 01 04.
Article en En | MEDLINE | ID: mdl-29276143
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Leucemia Mieloide Aguda / Nicho de Células Madre Límite: Animals / Humans Idioma: En Revista: Cell Stem Cell Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Leucemia Mieloide Aguda / Nicho de Células Madre Límite: Animals / Humans Idioma: En Revista: Cell Stem Cell Año: 2018 Tipo del documento: Article