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Design, synthesis, and evaluation of polyamine-memantine hybrids as NMDA channel blockers.
Kumamoto, Takuya; Nakajima, Marie; Uga, Reina; Ihayazaka, Naoko; Kashihara, Haruna; Katakawa, Kazuaki; Ishikawa, Tsutomu; Saiki, Ryotaro; Nishimura, Kazuhiro; Igarashi, Kazuei.
Afiliación
  • Kumamoto T; Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 732-8553, Japan. Electronic address: tkum632@hiroshima-u.ac.jp.
  • Nakajima M; Research Institute of Pharmaceutical Sciences, Musashino University, 1-1-20 Shinmachi, Nishitokyo 202-8585, Japan.
  • Uga R; Research Institute of Pharmaceutical Sciences, Musashino University, 1-1-20 Shinmachi, Nishitokyo 202-8585, Japan.
  • Ihayazaka N; Research Institute of Pharmaceutical Sciences, Musashino University, 1-1-20 Shinmachi, Nishitokyo 202-8585, Japan.
  • Kashihara H; Research Institute of Pharmaceutical Sciences, Musashino University, 1-1-20 Shinmachi, Nishitokyo 202-8585, Japan.
  • Katakawa K; Research Institute of Pharmaceutical Sciences, Musashino University, 1-1-20 Shinmachi, Nishitokyo 202-8585, Japan.
  • Ishikawa T; Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan.
  • Saiki R; Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan.
  • Nishimura K; Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan.
  • Igarashi K; Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan; Amine Pharma Research Institute, Innovation Plaza at Chiba University, 1-8-15 Inohana, Chuo-ku, Chiba 260-8675, Japan.
Bioorg Med Chem ; 26(3): 603-608, 2018 02 01.
Article en En | MEDLINE | ID: mdl-29277306
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poliaminas / Diseño de Fármacos / Memantina / Receptores de N-Metil-D-Aspartato / Fármacos Neuroprotectores Límite: Animals Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poliaminas / Diseño de Fármacos / Memantina / Receptores de N-Metil-D-Aspartato / Fármacos Neuroprotectores Límite: Animals Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article Pais de publicación: Reino Unido