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Efficient identification of compounds suppressing protein precipitation via solvent screening using serial deletion mutants of the target protein.
Yunoki, Kaori; Yoshinaga, Sosuke; Takeda, Mitsuhiro; Nagano, Ryohei; Tsuchiya, Yusuke; Sonoda, Akihiro; Tsuji, Tatsuichiro; Hirakane, Makoto; Toda, Etsuko; Terashima, Yuya; Matsushima, Kouji; Terasawa, Hiroaki.
Afiliación
  • Yunoki K; Department of Structural BioImaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Yoshinaga S; Department of Structural BioImaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Takeda M; Department of Structural BioImaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Nagano R; Department of Structural BioImaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Tsuchiya Y; Department of Structural BioImaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Sonoda A; Department of Structural BioImaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Tsuji T; Department of Structural BioImaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Hirakane M; Department of Structural BioImaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
  • Toda E; Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Terashima Y; Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Matsushima K; Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Terasawa H; Department of Structural BioImaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Genes Cells ; 23(2): 70-79, 2018 Feb.
Article en En | MEDLINE | ID: mdl-29292854
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Solventes / Eliminación de Secuencia / Proteínas de Complejo Poro Nuclear / Dominios y Motivos de Interacción de Proteínas / Estabilidad Proteica / Glicoles Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Genes Cells Asunto de la revista: BIOLOGIA MOLECULAR Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Solventes / Eliminación de Secuencia / Proteínas de Complejo Poro Nuclear / Dominios y Motivos de Interacción de Proteínas / Estabilidad Proteica / Glicoles Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Genes Cells Asunto de la revista: BIOLOGIA MOLECULAR Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido