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Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice.
Winn, Shelley R; Scherer, Tanja; Thöny, Beat; Ying, Ming; Martinez, Aurora; Weber, Sydney; Raber, Jacob; Harding, Cary O.
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  • Winn SR; Department of Medical and Molecular Genetics, Oregon Health & Science University, Mailstop L-103, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA.
  • Scherer T; Department of Pediatrics, University of Zurich, Steinweissstrasse 75, Zurich CH-8032, Switzerland.
  • Thöny B; Department of Pediatrics, University of Zurich, Steinweissstrasse 75, Zurich CH-8032, Switzerland.
  • Ying M; Department of Biomedicine, KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, 5009 Bergen, Norway.
  • Martinez A; Department of Biomedicine, KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, 5009 Bergen, Norway.
  • Weber S; Department of Behavioral Neuroscience, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA.
  • Raber J; Department of Behavioral Neuroscience, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA; Department of Neurology, Division of Neuroscience, ONPRC, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA; Department of Radia
  • Harding CO; Department of Medical and Molecular Genetics, Oregon Health & Science University, Mailstop L-103, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA. Electronic address: hardingc@ohsu.edu.
Mol Genet Metab ; 123(1): 6-20, 2018 01.
Article en En | MEDLINE | ID: mdl-29331172
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenilcetonurias / Enfermedades del Sistema Nervioso Central / Disfunción Cognitiva Límite: Animals / Humans Idioma: En Revista: Mol Genet Metab Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / METABOLISMO Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenilcetonurias / Enfermedades del Sistema Nervioso Central / Disfunción Cognitiva Límite: Animals / Humans Idioma: En Revista: Mol Genet Metab Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / METABOLISMO Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos