A new bis-γ-pyrone polypropionate from a marine pulmonate mollusc Onchidium struma.
J Asian Nat Prod Res
; 21(4): 384-390, 2019 Apr.
Article
en En
| MEDLINE
| ID: mdl-29357705
ABSTRACT
A new bis-γ-pyrone polypropionate compound onchidione II (1), together with three known compounds, was isolated from a marine pulmonate mollusc Onchidium struma, collected at Hainan Island of China. The structure of new compound was determined by extensive spectroscopic analyses including IR, 1D and 2D NMR techniques, and chemical methods. Compounds 1-4 were evaluated for their cytotoxicity against human tumor cell lines HepG-2, A549, and MCF-2. The results showed that compounds 1 and 2 were moderate cytotoxic against HepG-2, A549, and MCF-2 cell lines, with IC50 values from 13.2 to 22.4 µM.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pironas
/
Moluscos
/
Antineoplásicos
Límite:
Animals
Idioma:
En
Revista:
J Asian Nat Prod Res
Asunto de la revista:
BOTANICA
/
QUIMICA
Año:
2019
Tipo del documento:
Article
País de afiliación:
China