Systematic Review of Human and Animal Studies Examining the Efficacy and Safety of <i>N-</i>Acetylcysteine (NAC) and <i>N-</i>Acetylcysteine Amide (NACA) in Traumatic Brain Injury: Impact on Neurofunctional Outcome and Biomarkers of Oxidative Stress and Inflammation.

Bhatti, Junaid; Nascimento, Barto; Akhtar, Umbreen; Rhind, Shawn G; Tien, Homer; Nathens, Avery; da Luz, Luis Teodoro

Systematic Review of Human and Animal Studies Examining the Efficacy and Safety of N-Acetylcysteine (NAC) and N-Acetylcysteine Amide (NACA) in Traumatic Brain Injury: Impact on Neurofunctional Outcome and Biomarkers of Oxidative Stress and Inflammation.

Bhatti, Junaid; Nascimento, Barto; Akhtar, Umbreen; Rhind, Shawn G; Tien, Homer; Nathens, Avery; da Luz, Luis Teodoro.

Afiliación

Bhatti J; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Nascimento B; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Akhtar U; Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Rhind SG; Defense Research and Development Canada (DRDC), Toronto Research Centre, Toronto, ON, Canada.
Tien H; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Nathens A; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
da Luz LT; Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

Front Neurol ; 8: 744, 2017.

Article en En | MEDLINE | ID: mdl-29387038

Palabras clave

N-acetylcysteine; N-acetylcysteine amide; animal models; inflammation modulation; neurofunctional outcome; oxidative stress; traumatic brain injury

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Guideline / Prognostic_studies / Systematic_reviews Idioma: En Revista: Front Neurol Año: 2017 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Suiza

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