Macrophages and cytotoxic T cells infiltrate the destructed mitral tissue in Kawasaki disease.
BMJ Case Rep
; 20182018 Feb 02.
Article
en En
| MEDLINE
| ID: mdl-29420247
ABSTRACT
Kawasaki disease (KD) is an acute febrile systemic vasculitic syndrome especially affecting medium-sized arteries, including the coronary artery. Inflammation may involve all organs, and valvulitis is one of the cardiovascular complications that occurs in the acute phase of KD. However, details regarding the mechanism are unclear. An infant developed KD and severe mitral regurgitation with deformity and prolapse of the mitral tissue and underwent mitral valvotomy 1 year later. Histopathological study was conducted, and infiltrating cells consisted of mainly macrophages and cytotoxic T cells were found in resected mitral valve tissue. In addition, inflammation remained a long time after KD had developed.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Linfocitos T
/
Macrófagos
/
Válvula Mitral
/
Insuficiencia de la Válvula Mitral
/
Síndrome Mucocutáneo Linfonodular
Límite:
Humans
/
Infant
/
Male
Idioma:
En
Revista:
BMJ Case Rep
Año:
2018
Tipo del documento:
Article
País de afiliación:
Japón