Porcine interleukin-6 enhances the expression of CYP2C33 through a constitutive androstane receptor/retinoid X receptor-mediated pathway.

Xie, Lixia; He, Yucheng; Zhou, Xiaoqiao; Li, Xiaowen; Jin, Xiue; Wang, Xiliang; Shi, Deshi

Xie, Lixia; He, Yucheng; Zhou, Xiaoqiao; Li, Xiaowen; Jin, Xiue; Wang, Xiliang; Shi, Deshi.

Afiliación

Xie L; a State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine , Huazhong Agricultural University , Wuhan , People's Republic of China.
He Y; b Key Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine , Huazhong Agricultural University , Wuhan , People's Republic of China.
Zhou X; a State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine , Huazhong Agricultural University , Wuhan , People's Republic of China.
Li X; b Key Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine , Huazhong Agricultural University , Wuhan , People's Republic of China.
Jin X; a State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine , Huazhong Agricultural University , Wuhan , People's Republic of China.
Wang X; b Key Laboratory of Preventive Veterinary Medicine in Hubei Province, College of Veterinary Medicine , Huazhong Agricultural University , Wuhan , People's Republic of China.
Shi D; a State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine , Huazhong Agricultural University , Wuhan , People's Republic of China.

Xenobiotica ; 49(3): 257-264, 2019 Mar.

Article en En | MEDLINE | ID: mdl-29431552

Asunto(s)

Sistema Enzimático del Citocromo P-450/metabolismo; Interleucina-6/farmacología; Receptor X de Pregnano/fisiología; Receptores Citoplasmáticos y Nucleares/fisiología; Animales; Línea Celular; Receptor de Androstano Constitutivo; Sistema Enzimático del Citocromo P-450/genética; Regulación de la Expresión Génica/efectos de los fármacos; Hepatocitos/metabolismo; Inactivación Metabólica; Interleucina-6/metabolismo; Interleucina-6/fisiología; Receptor X de Pregnano/genética; Receptor X de Pregnano/metabolismo; ARN Mensajero/metabolismo; Receptores Citoplasmáticos y Nucleares/genética; Receptores Citoplasmáticos y Nucleares/metabolismo; Porcinos; Xenobióticos/metabolismo

Palabras clave

CYP2C33; Drug-metabolizing enzymes; constitutive androstane receptor; hepatocytes; interleukin-6

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interleucina-6 / Receptores Citoplasmáticos y Nucleares / Sistema Enzimático del Citocromo P-450 / Receptor X de Pregnano Límite: Animals Idioma: En Revista: Xenobiotica Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido

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