[Immune complex hyperuricemic nephritis: aspects of its morphology and pathogenesis]. / Immunokompleksnyi giperurikemicheskii nefrit: nekotorye aspekty morfologii i patogeneza.
Ter Arkh
; 58(8): 97-101, 1986.
Article
en Ru
| MEDLINE
| ID: mdl-2945281
ABSTRACT
The authors described the results of an immunohistochemical, electron microscopic and morphometric study of the kidney bioptates of 45 patients with latent glomerulonephritis with hyperuricemia, 8 patients with primary gout and 12 patients with latent glomerulonephritis without hyperuricemia. Two possible variants of the involvement of the renal glomerula were revealed against a background of purine metabolism typical immunocomplex glomerulonephritis and the so called "reactive" mesangial changes. The expression of interstitial changes (by the results of histometric investigation) was maximum in gout, slightly less in latent nephritis with hyperuricemia and minimum in nephritis without hyperuricemia. The authors emphasized the possibility of immunocomplex nephritis as one of the variants of renal lesion in gout and hyperuricemia and the necessity of specifying therapeutic modalities to be used in this condition including general nephrological approaches to the treatment of latent nephropathies.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ácido Úrico
/
Enfermedades del Complejo Inmune
/
Nefritis
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
Ru
Revista:
Ter Arkh
Año:
1986
Tipo del documento:
Article