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Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development.
Sung, Yun-Chieh; Liu, Ya-Chi; Chao, Po-Han; Chang, Chih-Chun; Jin, Pei-Ru; Lin, Ts-Ting; Lin, Ja-An; Cheng, Hui-Teng; Wang, Jane; Lai, Charles P; Chen, Ling-Hsuan; Wu, Anthony Y; Ho, Ting-Lun; Chiang, Tsaiyu; Gao, Dong-Yu; Duda, Dan G; Chen, Yunching.
Afiliación
  • Sung YC; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
  • Liu YC; Department of Chemical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
  • Chao PH; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
  • Chang CC; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
  • Jin PR; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
  • Lin TT; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
  • Lin JA; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
  • Cheng HT; Department of Biostatistics, University of North Caroline at Chapel Hill.
  • Wang J; Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsin Chu City 30059, Taiwan.
  • Lai CP; Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan.
  • Chen LH; Department of Chemical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
  • Wu AY; Institute of Atomic and Molecular Sciences (IAMS), Academia Sinica, National Taiwan University, Taipei, Taiwan.
  • Ho TL; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
  • Chiang T; Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsin Chu City 30059, Taiwan.
  • Gao DY; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
  • Duda DG; Institute of Atomic and Molecular Sciences (IAMS), Academia Sinica, National Taiwan University, Taipei, Taiwan.
  • Chen Y; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
Theranostics ; 8(4): 894-905, 2018.
Article en En | MEDLINE | ID: mdl-29463989
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Receptores CXCR4 / Inhibidores de Proteínas Quinasas / Nanopartículas / Sorafenib / Cirrosis Hepática / Neoplasias Hepáticas Límite: Animals Idioma: En Revista: Theranostics Año: 2018 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Australia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Receptores CXCR4 / Inhibidores de Proteínas Quinasas / Nanopartículas / Sorafenib / Cirrosis Hepática / Neoplasias Hepáticas Límite: Animals Idioma: En Revista: Theranostics Año: 2018 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Australia